Pd-Catalyzed para-selective C-H difluoromethylation of aromatic carbonyls.
Chem Commun (Camb)
; 55(14): 2019-2022, 2019 Feb 12.
Article
em En
| MEDLINE
| ID: mdl-30564815
ABSTRACT
A novel palladium catalyzed highly para-selective C-H difluoromethylation of electron-deficient aromatic carbonyls was developed. Diverse substituted aromatic ketones and benzoates were selectively difluoromethylated at the remote para-site of carbonyl groups in moderate to good yields. Moreover, the difuoromethylation was also compatible with several complex bioactive molecules.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article