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Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience.
Zakrzewska, Joanna M; Palmer, Joanne; Bendtsen, Lars; Di Stefano, Giulia; Ettlin, Dominik A; Maarbjerg, Stine; Obermann, Mark; Morisset, Valerie; Steiner, Deb; Tate, Simon; Cruccu, Giorgio.
Afiliação
  • Zakrzewska JM; Facial Pain Unit, Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, University College London Hospitals NHS Foundation Trust/University College London, London, UK. j.Zakrzewska@ucl.ac.uk.
  • Palmer J; Eastman Dental Hospital, 256 Gray's Inn Road, London, UK. j.Zakrzewska@ucl.ac.uk.
  • Bendtsen L; Pain Management Centre, University College London Hospitals NHS Foundation Trust, London, UK. j.Zakrzewska@ucl.ac.uk.
  • Di Stefano G; Convergence Pharmaceuticals Ltd, Cambridge, UK.
  • Ettlin DA; Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Valdemar Hansens Vej 5, 2600, Glostrup, Denmark.
  • Maarbjerg S; Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy.
  • Obermann M; Interdisciplinary Orofacial Pain Unit, Clinic of Masticatory Disorders, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
  • Morisset V; Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Valdemar Hansens Vej 5, 2600, Glostrup, Denmark.
  • Steiner D; Department of Neurology and German Headache Center, University of Duisburg-Essen, Essen, Germany.
  • Tate S; Center for Neurology, Asklepios Hospitals Schildautal, Seesen, Germany.
  • Cruccu G; Convergence Pharmaceuticals Ltd, Cambridge, UK.
Trials ; 19(1): 704, 2018 Dec 27.
Article em En | MEDLINE | ID: mdl-30587219
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nervo Trigêmeo / Neuralgia do Trigêmeo / Seleção de Pacientes / Bloqueadores dos Canais de Sódio / Doenças Raras / Analgésicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Humans / Middle aged País/Região como assunto: Africa / Europa Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nervo Trigêmeo / Neuralgia do Trigêmeo / Seleção de Pacientes / Bloqueadores dos Canais de Sódio / Doenças Raras / Analgésicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Humans / Middle aged País/Região como assunto: Africa / Europa Idioma: En Ano de publicação: 2018 Tipo de documento: Article