Investigation of the influence of xenoreactive antibodies on activation of complement and coagulation in an ex vivo perfusion animal study using porcine kidneys.

Ramackers, Wolf; Werwitzke, Sonja; Klose, Johannes; Friedrich, Lars; Johanning, Kai; Bergmann, Sabine; Klempnauer, Jürgen; Winkler, Michael; Tiede, Andreas

Ramackers, Wolf; Werwitzke, Sonja; Klose, Johannes; Friedrich, Lars; Johanning, Kai; Bergmann, Sabine; Klempnauer, Jürgen; Winkler, Michael; Tiede, Andreas.

Afiliação

Ramackers W; Department of General and Transplantation Surgery, Hannover Medical School, Hannover, Germany.
Werwitzke S; Department of Hematology Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Klose J; Department of Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Friedrich L; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Johanning K; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Bergmann S; Department of General and Transplantation Surgery, Hannover Medical School, Hannover, Germany.
Klempnauer J; Department of General and Transplantation Surgery, Hannover Medical School, Hannover, Germany.
Winkler M; Department of General and Transplantation Surgery, Hannover Medical School, Hannover, Germany.
Tiede A; Department of Hematology Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

Transpl Int ; 32(5): 546-556, 2019 May.

Article em En | MEDLINE | ID: mdl-30597634

Assuntos

Proteínas do Sistema Complemento/química; Transplante de Rim; Microangiopatias Trombóticas/imunologia; Transplante Heterólogo; Animais; Anticorpos; Ativação do Complemento; Células Endoteliais/imunologia; Produtos de Degradação da Fibrina e do Fibrinogênio/imunologia; Rejeição de Enxerto/imunologia; Humanos; Imunoglobulina G/imunologia; Imunoglobulina M/imunologia; Técnicas Imunológicas; Inflamação; Rim/patologia; Perfusão; Primatas; Suínos; Fatores de Tempo

Palavras-chave

coagulation; ex vivo perfusion; porcine kidneys; xenotransplantation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante Heterólogo / Proteínas do Sistema Complemento / Transplante de Rim / Microangiopatias Trombóticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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