Structural basis of Notch recognition by human Î³-secretase.

Yang, Guanghui; Zhou, Rui; Zhou, Qiang; Guo, Xuefei; Yan, Chuangye; Ke, Meng; Lei, Jianlin; Shi, Yigong

Yang, Guanghui; Zhou, Rui; Zhou, Qiang; Guo, Xuefei; Yan, Chuangye; Ke, Meng; Lei, Jianlin; Shi, Yigong.

Afiliação

Yang G; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Zhou R; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Zhou Q; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Guo X; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, China.
Yan C; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Ke M; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Lei J; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Shi Y; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.

Nature ; 565(7738): 192-197, 2019 01.

Article em En | MEDLINE | ID: mdl-30598546

Assuntos

Secretases da Proteína Precursora do Amiloide/metabolismo; Secretases da Proteína Precursora do Amiloide/ultraestrutura; Microscopia Crioeletrônica; Receptores Notch/metabolismo; Receptores Notch/ultraestrutura; Sequência de Aminoácidos; Secretases da Proteína Precursora do Amiloide/química; Precursor de Proteína beta-Amiloide/química; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Humanos; Camundongos; Modelos Moleculares; Ligação Proteica; Receptores Notch/química; Especificidade por Substrato

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microscopia Crioeletrônica / Receptores Notch / Secretases da Proteína Precursora do Amiloide Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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