Prevalence and characterization of ATM germline mutations in Chinese BRCA1/2-negative breast cancer patients.

Yang, Ziguo; Ouyang, Tao; Li, Jinfeng; Wang, Tianfeng; Fan, Zhaoqing; Fan, Tie; Lin, Benyao; Zhang, Juan; Xie, Yuntao

Yang, Ziguo; Ouyang, Tao; Li, Jinfeng; Wang, Tianfeng; Fan, Zhaoqing; Fan, Tie; Lin, Benyao; Zhang, Juan; Xie, Yuntao.

Afiliação

Yang Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Ouyang T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Li J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Wang T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Fan Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Fan T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Lin B; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China.
Zhang J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China. zhangjuan100@126.com.
Xie Y; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, 100142, Beijing, People's Republic of China. zlxyt2@bjmu.edu.cn.

Breast Cancer Res Treat ; 174(3): 639-647, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30607632

Assuntos

Povo Asiático/genética; Proteínas Mutadas de Ataxia Telangiectasia/genética; Neoplasias da Mama/genética; Mutação em Linhagem Germinativa; Neoplasias Ovarianas/genética; Adulto; Proteína BRCA1/genética; Proteína BRCA2/genética; Neoplasias da Mama/metabolismo; China; Feminino; Predisposição Genética para Doença; Heterozigoto; Humanos; Pessoa de Meia-Idade; Linhagem; Reação em Cadeia da Polimerase; Prevalência; Receptores de Estrogênio/metabolismo; Receptores de Progesterona/metabolismo; Análise de Sequência de DNA

Palavras-chave

ATM gene; Breast cancer; Chinese population; Germline mutation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Mutação em Linhagem Germinativa / Povo Asiático / Proteínas Mutadas de Ataxia Telangiectasia Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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