Subchronic administration of aripiprazole improves fear extinction retrieval of Pavlovian conditioning paradigm in rats experiencing psychological trauma.

Lin, Chen-Cheng; Chang, Hsin-An; Tai, Yueh-Ming; Chen, Tsung-Yen; Wan, Fang-Jung; Chang, Chuan-Chia; Tung, Che-Se; Liu, Yia-Ping

Lin, Chen-Cheng; Chang, Hsin-An; Tai, Yueh-Ming; Chen, Tsung-Yen; Wan, Fang-Jung; Chang, Chuan-Chia; Tung, Che-Se; Liu, Yia-Ping.

Afiliação

Lin CC; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, 11490, Taiwan; Department of Psychiatry, Cheng Hsin General Hospital, Taipei, 11220, Taiwan.
Chang HA; Department of Psychiatry, Tri-Service General Hospital, Taipei, 11490, Taiwan.
Tai YM; Department of Psychiatry, Beitou Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chen TY; Department of Psychiatry, Cheng Hsin General Hospital, Taipei, 11220, Taiwan.
Wan FJ; Department of Psychiatry, Tri-Service General Hospital, Taipei, 11490, Taiwan.
Chang CC; Department of Psychiatry, Tri-Service General Hospital, Taipei, 11490, Taiwan.
Tung CS; Division of Medical Research and Education, Cheng Hsin General Hospital, Taipei, 11220, Taiwan.
Liu YP; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, 11490, Taiwan; Department of Psychiatry, Cheng Hsin General Hospital, Taipei, 11220, Taiwan; Department of Psychiatry, Tri-Service General Hospital, Taipei, 11490, Taiwan; Laboratory of Cognitive Neuroscience, Department o

Behav Brain Res ; 362: 181-187, 2019 04 19.

Article em En | MEDLINE | ID: mdl-30610908

Assuntos

Aripiprazol/farmacologia; Medo/efeitos dos fármacos; Memória/efeitos dos fármacos; Trauma Psicológico/tratamento farmacológico; Tonsila do Cerebelo/efeitos dos fármacos; Animais; Aripiprazol/administração & dosagem; Condicionamento Clássico/fisiologia; Modelos Animais de Doenças; Extinção Psicológica/fisiologia; Medo/fisiologia; Masculino; Ratos Sprague-Dawley; Transtornos de Estresse Pós-Traumáticos/tratamento farmacológico; Transtornos de Estresse Pós-Traumáticos/fisiopatologia; Estresse Psicológico/tratamento farmacológico

Palavras-chave

Amygdala; Aripiprazole; Dopamine; Fear memory; PTSD

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medo / Aripiprazol / Trauma Psicológico / Memória Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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