Vascularized composite allograft rejection is delayed by infusion of IFN-Î³-conditioned BMSCs through upregulating PD-L1.

Wang, Yaojun; Xi, Yunfeng; Han, Fu; Liu, Yang; Li, Na; Ren, Zhongliang; Xue, Jiajie; Guo, Lei; Hu, Dahai

Wang, Yaojun; Xi, Yunfeng; Han, Fu; Liu, Yang; Li, Na; Ren, Zhongliang; Xue, Jiajie; Guo, Lei; Hu, Dahai.

Afiliação

Wang Y; Department of Burn and Plastic Surgery, Yulin No.2 Hospital, Yulin, 719000, China.
Xi Y; Department of Burn, Xijing Hospital Affiliated to the Fourth Military Medical University, No.127 West Changle Road,, Xi'an, 710032, China.
Han F; Department of Burn and Plastic Surgery, Yulin First Hospital, Yulin, 719000, China.
Liu Y; Department of Burn, Xijing Hospital Affiliated to the Fourth Military Medical University, No.127 West Changle Road,, Xi'an, 710032, China.
Li N; Department of Burn, Xijing Hospital Affiliated to the Fourth Military Medical University, No.127 West Changle Road,, Xi'an, 710032, China.
Ren Z; Department of Burn, Xijing Hospital Affiliated to the Fourth Military Medical University, No.127 West Changle Road,, Xi'an, 710032, China.
Xue J; Department of Burn and Plastic Surgery, Yulin No.2 Hospital, Yulin, 719000, China.
Guo L; Department of Burn and Plastic Surgery, Yulin No.2 Hospital, Yulin, 719000, China.
Hu D; Department of Burn and Plastic Surgery, Yulin No.2 Hospital, Yulin, 719000, China.

Cell Tissue Res ; 376(2): 211-220, 2019 May.

Article em En | MEDLINE | ID: mdl-30613905

Assuntos

Antígeno B7-H1/imunologia; Aloenxertos Compostos/imunologia; Rejeição de Enxerto/prevenção & controle; Interferon gama/farmacologia; Células-Tronco Mesenquimais/efeitos dos fármacos; Linfócitos T/imunologia; Animais; Proliferação de Células/efeitos dos fármacos; Aloenxertos Compostos/efeitos dos fármacos; Rejeição de Enxerto/imunologia; Membro Posterior; Ativação Linfocitária/efeitos dos fármacos; Células-Tronco Mesenquimais/imunologia; Ratos Endogâmicos BN; Ratos Endogâmicos Lew; Linfócitos T/efeitos dos fármacos

Palavras-chave

Allograft rejection; BMSC; IFN-Î³; PD-L1; T cell proliferation and activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Interferon gama / Células-Tronco Mesenquimais / Antígeno B7-H1 / Aloenxertos Compostos / Rejeição de Enxerto Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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