Low-pass Whole-genome Sequencing of Circulating Cell-free DNA Demonstrates Dynamic Changes in Genomic Copy Number in a Squamous Lung Cancer Clinical Cohort.

Chen, Xiaoji; Chang, Ching-Wei; Spoerke, Jill M; Yoh, Kathryn E; Kapoor, Vidushi; Baudo, Charles; Aimi, Junko; Yu, Mamie; Liang-Chu, May M Y; Suttmann, Rebecca; Huw, Ling-Yuh; Gendreau, Steven; Cummings, Craig; Lackner, Mark R

Chen, Xiaoji; Chang, Ching-Wei; Spoerke, Jill M; Yoh, Kathryn E; Kapoor, Vidushi; Baudo, Charles; Aimi, Junko; Yu, Mamie; Liang-Chu, May M Y; Suttmann, Rebecca; Huw, Ling-Yuh; Gendreau, Steven; Cummings, Craig; Lackner, Mark R.

Afiliação

Chen X; Department of Oncology Biomarker Development, Genentech, South San Francisco, California. marklackner01@gmail.com xiaojichen76@gmail.com.
Chang CW; Department of Biostatistics, Genentech, South San Francisco, California.
Spoerke JM; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Yoh KE; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Kapoor V; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Baudo C; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Aimi J; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Yu M; Department of Discovery Oncology, Genentech, South San Francisco, California.
Liang-Chu MMY; Department of Discovery Oncology, Genentech, South San Francisco, California.
Suttmann R; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Huw LY; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Gendreau S; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Cummings C; Department of Oncology Biomarker Development, Genentech, South San Francisco, California.
Lackner MR; Department of Oncology Biomarker Development, Genentech, South San Francisco, California. marklackner01@gmail.com xiaojichen76@gmail.com.

Clin Cancer Res ; 25(7): 2254-2263, 2019 04 01.

Article em En | MEDLINE | ID: mdl-30617129

Assuntos

Biomarcadores Tumorais; Carcinoma de Células Escamosas/genética; DNA Tumoral Circulante; Genoma Humano; Genômica; Neoplasias Pulmonares/genética; Carcinoma de Células Escamosas/diagnóstico; Carcinoma de Células Escamosas/tratamento farmacológico; Carcinoma de Células Escamosas/mortalidade; Linhagem Celular Tumoral; Estudos de Coortes; Variações do Número de Cópias de DNA; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Resistencia a Medicamentos Antineoplásicos/genética; Genômica/métodos; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Neoplasias Pulmonares/diagnóstico; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/mortalidade; Terapia de Alvo Molecular; Polimorfismo de Nucleotídeo Único; Prognóstico; Análise de Sequência de DNA; Sequenciamento Completo do Genoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Biomarcadores Tumorais / Genoma Humano / Genômica / DNA Tumoral Circulante / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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