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Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.
Akilesh, Holly M; Buechler, Matthew B; Duggan, Jeffrey M; Hahn, William O; Matta, Bharati; Sun, Xizhang; Gessay, Griffin; Whalen, Elizabeth; Mason, Michael; Presnell, Scott R; Elkon, Keith B; Lacy-Hulbert, Adam; Barnes, Betsy J; Pepper, Marion; Hamerman, Jessica A.
Afiliação
  • Akilesh HM; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Buechler MB; Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Duggan JM; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Hahn WO; Department of Immunology, University of Washington, Seattle, WA, USA.
  • Matta B; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Sun X; Department of Immunology, University of Washington, Seattle, WA, USA.
  • Gessay G; Department of Immunology, University of Washington, Seattle, WA, USA.
  • Whalen E; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Mason M; Center for Autoimmune, Musculoskeletal and Hematopoietic Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA.
  • Presnell SR; Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Elkon KB; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Lacy-Hulbert A; Systems Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Barnes BJ; Systems Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Pepper M; Systems Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Hamerman JA; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
Science ; 363(6423)2019 01 11.
Article em En | MEDLINE | ID: mdl-30630901

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fagócitos / Glicoproteínas de Membrana / Transdução de Sinais / Receptor Toll-Like 9 / Receptor 7 Toll-Like / Síndrome de Ativação Macrofágica / Anemia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fagócitos / Glicoproteínas de Membrana / Transdução de Sinais / Receptor Toll-Like 9 / Receptor 7 Toll-Like / Síndrome de Ativação Macrofágica / Anemia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article