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The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis.
Villanueva, Francisco; Araya, Hector; Briceño, Pedro; Varela, Nelson; Stevenson, Andres; Jerez, Sofia; Tempio, Fabian; Chnaiderman, Jonas; Perez, Carola; Villarroel, Milena; Concha, Emma; Khani, Farzaneh; Thaler, Roman; Salazar-Onfray, Flavio; Stein, Gary S; van Wijnen, Andre J; Galindo, Mario.
Afiliação
  • Villanueva F; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Araya H; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Briceño P; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Varela N; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Stevenson A; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Jerez S; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Tempio F; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Chnaiderman J; Department of Medical Technology, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Perez C; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Villarroel M; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Concha E; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Khani F; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Thaler R; Millennium Institute on Immunology and Immunotherapy, University of Chile, Santiago, Chile.
  • Salazar-Onfray F; Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Stein GS; Program of Virology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • van Wijnen AJ; Laboratory Animal Facility, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
  • Galindo M; Department of Oncology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
J Cell Physiol ; 234(8): 13659-13679, 2019 08.
Article em En | MEDLINE | ID: mdl-30637720
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Regulação Neoplásica da Expressão Gênica / Subunidade alfa 1 de Fator de Ligação ao Core / Osteopontina / Invasividade Neoplásica Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Regulação Neoplásica da Expressão Gênica / Subunidade alfa 1 de Fator de Ligação ao Core / Osteopontina / Invasividade Neoplásica Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article