C-type natriuretic peptide regulates sperm capacitation by the cGMP/PKG signalling pathway via Ca<sup>2+</sup> influx and tyrosine phosphorylation.

Wu, Kejia; Mei, Chunlei; Chen, Yao; Guo, Lidan; Yu, Yuejin; Huang, Donghui

C-type natriuretic peptide regulates sperm capacitation by the cGMP/PKG signalling pathway via Ca²⁺ influx and tyrosine phosphorylation.

Wu, Kejia; Mei, Chunlei; Chen, Yao; Guo, Lidan; Yu, Yuejin; Huang, Donghui.

Afiliação

Wu K; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
Mei C; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chen Y; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Reproductive Medicine Centre of Jingzhou Central Hospital, Jingzhou 434000, China.
Guo L; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yu Y; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Huang D; Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: jhsyyjs@126.com.

Reprod Biomed Online ; 38(3): 289-299, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30655075

Assuntos

Cálcio/metabolismo; Proteínas Quinases Dependentes de GMP Cíclico/metabolismo; GMP Cíclico/metabolismo; Peptídeo Natriurético Tipo C/metabolismo; Transdução de Sinais/fisiologia; Capacitação Espermática/fisiologia; Animais; Colo do Útero/metabolismo; Feminino; Humanos; Masculino; Oviductos/metabolismo; Fosforilação; Ratos; Ratos Sprague-Dawley; Receptores do Fator Natriurético Atrial/metabolismo; Espermatozoides/metabolismo; Tirosina/metabolismo

Palavras-chave

C-type natriuretic peptide; CGMP/PKG signalling pathway; Ca(2+); Sperm capacitation; Tyrosine phosphorylation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Capacitação Espermática / Transdução de Sinais / Cálcio / Proteínas Quinases Dependentes de GMP Cíclico / GMP Cíclico / Peptídeo Natriurético Tipo C Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google