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Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Xu, Hui; Li, Tianbo; Rohou, Alexis; Arthur, Christopher P; Tzakoniati, Foteini; Wong, Evera; Estevez, Alberto; Kugel, Christine; Franke, Yvonne; Chen, Jun; Ciferri, Claudio; Hackos, David H; Koth, Christopher M; Payandeh, Jian.
Afiliação
  • Xu H; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Li T; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA. Electronic address: li.tianbo@gene.com.
  • Rohou A; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA. Electronic address: rohou.alexis@gene.com.
  • Arthur CP; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Tzakoniati F; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Wong E; Department of Neuroscience, Genentech, South San Francisco, CA 94080, USA.
  • Estevez A; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Kugel C; Department of Biomolecular Resources, Genentech, South San Francisco, CA 94080, USA.
  • Franke Y; Department of Biomolecular Resources, Genentech, South San Francisco, CA 94080, USA.
  • Chen J; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Ciferri C; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Hackos DH; Department of Neuroscience, Genentech, South San Francisco, CA 94080, USA. Electronic address: hackos.david@gene.com.
  • Koth CM; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA. Electronic address: koth.christopher@gene.com.
  • Payandeh J; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA. Electronic address: payandeh.jian@gene.com.
Cell ; 176(4): 702-715.e14, 2019 02 07.
Article em En | MEDLINE | ID: mdl-30661758
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Venenos de Aranha / Canal de Sódio Disparado por Voltagem NAV1.7 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Venenos de Aranha / Canal de Sódio Disparado por Voltagem NAV1.7 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article