Inhibition of multiple myeloma­derived exosomes uptake suppresses the functional response in bone marrow stromal cell.

Zheng, Yongjiang; Tu, Chenggong; Zhang, Jingwen; Wang, Jinheng

Inhibition of multiple myelomaderived exosomes uptake suppresses the functional response in bone marrow stromal cell.

Zheng, Yongjiang; Tu, Chenggong; Zhang, Jingwen; Wang, Jinheng.

Afiliação

Zheng Y; Department of Hematology, The Third Affiliated Hospital of Sun YatSen University, Guangzhou, Guangdong 510630, P.R. China.
Tu C; Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.
Zhang J; Department of Hematology, The Third Affiliated Hospital of Sun YatSen University, Guangzhou, Guangdong 510630, P.R. China.
Wang J; Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China.

Int J Oncol ; 54(3): 1061-1070, 2019 03.

Article em En | MEDLINE | ID: mdl-30664188

Assuntos

Endocitose; Exossomos/patologia; Células-Tronco Mesenquimais/patologia; Mieloma Múltiplo/patologia; Caveolinas/antagonistas & inibidores; Caveolinas/metabolismo; Linhagem Celular Tumoral; Sobrevivência Celular; Células Cultivadas; Endocitose/efeitos dos fármacos; Exossomos/metabolismo; Heparina/farmacologia; Humanos; Fusão de Membrana; Mieloma Múltiplo/metabolismo; Pinocitose; Transdução de Sinais; Temperatura

Palavras-chave

exosomes; uptake; endocytosis; multiple myeloma; bone marrow stromal cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endocitose / Exossomos / Células-Tronco Mesenquimais / Mieloma Múltiplo Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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