MicroRNA-6809-5p mediates luteolin-induced anticancer effects against hepatoma by targeting flotillin 1.

Yang, Pei-Wei; Lu, Zheng-Yu; Pan, Qing; Chen, Ting-Ting; Feng, Xiao-Jun; Wang, Shou-Mei; Pan, Yun-Cui; Zhu, Ming-Hua; Zhang, Shu-Hui

Yang, Pei-Wei; Lu, Zheng-Yu; Pan, Qing; Chen, Ting-Ting; Feng, Xiao-Jun; Wang, Shou-Mei; Pan, Yun-Cui; Zhu, Ming-Hua; Zhang, Shu-Hui.

Afiliação

Yang PW; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lu ZY; Department of Neurology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: lu_zhengyu@hotmail.com.
Pan Q; Department of Pathology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Chen TT; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Feng XJ; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang SM; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pan YC; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhu MH; Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Zhang SH; Department of Pathology, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: zhangshuhui100@sohu.com.

Phytomedicine ; 57: 18-29, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30668319

Assuntos

Antineoplásicos/farmacologia; Carcinoma Hepatocelular/tratamento farmacológico; Neoplasias Hepáticas/tratamento farmacológico; Luteolina/farmacologia; MicroRNAs/genética; Animais; Apoptose/genética; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Proliferação de Células/genética; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Células Hep G2; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patologia; Proteínas de Membrana/genética; Camundongos Nus; Transdução de Sinais; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Flotillin 1; Hepatocellular carcinoma; Luteolin; MAPK pathway; miR-6809-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Luteolina / Neoplasias Hepáticas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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