Vasoprotective Functions of High-Density Lipoproteins Relevant to Alzheimer's Disease Are Partially Conserved in Apolipoprotein B-Depleted Plasma.

Button, Emily B; Gilmour, Megan; Cheema, Harleen K; Martin, Emma M; Agbay, Andrew; Robert, Jérôme; Wellington, Cheryl L

Button, Emily B; Gilmour, Megan; Cheema, Harleen K; Martin, Emma M; Agbay, Andrew; Robert, Jérôme; Wellington, Cheryl L.

Afiliação

Button EB; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. ebbutton@mail.ubc.ca.
Gilmour M; Djavad Mowafaghian Centre for Brain Health, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. ebbutton@mail.ubc.ca.
Cheema HK; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. meg.gilmour@gmail.com.
Martin EM; Djavad Mowafaghian Centre for Brain Health, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. meg.gilmour@gmail.com.
Agbay A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. harleencheema@hotmail.com.
Robert J; Djavad Mowafaghian Centre for Brain Health, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. harleencheema@hotmail.com.
Wellington CL; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. emmarie@mail.ubc.ca.

Int J Mol Sci ; 20(3)2019 Jan 22.

Article em En | MEDLINE | ID: mdl-30678190

Assuntos

Doença de Alzheimer/sangue; Doença de Alzheimer/metabolismo; Apolipoproteínas B/deficiência; Lipoproteínas HDL/sangue; Lipoproteínas HDL/metabolismo; Plasma/metabolismo; Adulto; Peptídeos beta-Amiloides/metabolismo; Bioengenharia; Barreira Hematoencefálica/metabolismo; Células Cultivadas; Angiopatia Amiloide Cerebral/sangue; Angiopatia Amiloide Cerebral/metabolismo; Células Endoteliais/metabolismo; Ensaio de Imunoadsorção Enzimática; Feminino; Humanos; Inflamação/sangue; Inflamação/metabolismo; Masculino; Monócitos/citologia; Monócitos/metabolismo; Óxido Nítrico/metabolismo; Adulto Jovem

Palavras-chave

Alzheimer's disease; amyloid beta (Aß); blood-brain barrier (BBB); cerebral amyloid angiopathy (CAA); cerebrovasculature; endothelial cell; high-density lipoprotein (HDL); inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas B / Plasma / Doença de Alzheimer / Lipoproteínas HDL Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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