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Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
Van Lam van, Thuy; Ivanova, Teodora; Hardes, Kornelia; Heindl, Miriam Ruth; Morty, Rory E; Böttcher-Friebertshäuser, Eva; Lindberg, Iris; Than, Manuel E; Dahms, Sven O; Steinmetzer, Torsten.
Afiliação
  • Van Lam van T; Institute of Pharmaceutical Chemistry, Philipps University, Marbacher Weg 6, 35032, Marburg, Germany.
  • Ivanova T; Institute of Pharmaceutical Chemistry, Philipps University, Marbacher Weg 6, 35032, Marburg, Germany.
  • Hardes K; Institute of Pharmaceutical Chemistry, Philipps University, Marbacher Weg 6, 35032, Marburg, Germany.
  • Heindl MR; Institute of Virology, Philipps University, Hans-Meerwein-Str. 2, 35043, Marburg, Germany.
  • Morty RE; Department of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
  • Böttcher-Friebertshäuser E; Institute of Virology, Philipps University, Hans-Meerwein-Str. 2, 35043, Marburg, Germany.
  • Lindberg I; Department of Anatomy and Neurobiology, University of Maryland Medical School, Baltimore, MD, 21201, USA.
  • Than ME; Protein Crystallography Group, Leibniz Institute on Aging-Fritz Lipmann Institute, Beutenbergstr. 11, 07745, Jena, Germany.
  • Dahms SO; Department of Biosciences, University of Salzburg, Billrothstrasse 11, 5020, Salzburg, Austria.
  • Steinmetzer T; Institute of Pharmaceutical Chemistry, Philipps University, Marbacher Weg 6, 35032, Marburg, Germany.
ChemMedChem ; 14(6): 673-685, 2019 03 22.
Article em En | MEDLINE | ID: mdl-30680958
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Pró-Proteína Convertases / Compostos Macrocíclicos / Inibidores Enzimáticos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Pró-Proteína Convertases / Compostos Macrocíclicos / Inibidores Enzimáticos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article