Advances in Micropipette Aspiration: Applications in Cell Biomechanics, Models, and Extended Studies.
Biophys J
; 116(4): 587-594, 2019 02 19.
Article
em En
| MEDLINE
| ID: mdl-30683304
ABSTRACT
With five decades of sustained application, micropipette aspiration has enabled a wide range of biomechanical studies in the field of cell mechanics. Here, we provide an update on the use of the technique, with a focus on recent developments in the analysis of the experiments, innovative microaspiration-based approaches, and applications in a broad variety of cell types. We first recapitulate experimental variations of the technique. We then discuss analysis models focusing on important limitations of widely used biomechanical models, which underpin the urge to adopt the appropriate ones to avoid misleading conclusions. The possibilities of performing different studies on the same cell are also considered.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células
/
Fenômenos Mecânicos
/
Micromanipulação
/
Modelos Biológicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article