CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGÎ³.

Fan, Jiao; Liu, Lifeng; Liu, Qingyan; Cui, Yu; Yao, Binwei; Zhang, Minghua; Gao, Yabing; Fu, Yesheng; Dai, Hongmiao; Pan, Jingkun; Qiu, Ya; Liu, Cui Hua; He, Fuchu; Wang, Yu; Zhang, Lingqiang

Fan, Jiao; Liu, Lifeng; Liu, Qingyan; Cui, Yu; Yao, Binwei; Zhang, Minghua; Gao, Yabing; Fu, Yesheng; Dai, Hongmiao; Pan, Jingkun; Qiu, Ya; Liu, Cui Hua; He, Fuchu; Wang, Yu; Zhang, Lingqiang.

Afiliação

Fan J; State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China.
Liu L; Institute of Geriatrics, National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing, 100853, China.
Liu Q; Department of Cardiology, Chinese PLA General Hospital, Beijing, 100853, China.
Cui Y; Center of Therapeutic Research for Liver Cancer, 302 Military Hospital of China, Beijing, 100039, China.
Yao B; State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China.
Zhang M; Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Gao Y; Clinical Pharmacy Laboratory, Chinese PLA General Hospital, Beijing, 100853, China.
Fu Y; Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Dai H; State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China.
Pan J; State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China.
Qiu Y; Institute of Geriatrics, National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing, 100853, China.
Liu CH; Institute of Geriatrics, National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing, 100853, China.
He F; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
Wang Y; State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China.
Zhang L; Department of Cardiology, Chinese PLA General Hospital, Beijing, 100853, China. wangyuheart@163.com.

Nat Commun ; 10(1): 425, 2019 01 25.

Article em En | MEDLINE | ID: mdl-30683852

Assuntos

Aterosclerose/genética; Autoantígenos/genética; Proteínas de Transporte/genética; Células Espumosas/metabolismo; Fator 1 de Transcrição de Octâmero/genética; Placa Aterosclerótica/genética; Complexo de Endopeptidases do Proteassoma/genética; Animais; Aterosclerose/metabolismo; Aterosclerose/patologia; Autoantígenos/metabolismo; Transplante de Medula Óssea; Antígenos CD36/genética; Antígenos CD36/metabolismo; Proteínas de Transporte/antagonistas & inibidores; Proteínas de Transporte/metabolismo; Dieta Ocidental; Modelos Animais de Doenças; Células Espumosas/patologia; Regulação da Expressão Gênica; Células HEK293; Humanos; Lipoproteínas LDL/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fator 1 de Transcrição de Octâmero/metabolismo; Placa Aterosclerótica/metabolismo; Placa Aterosclerótica/patologia; Complexo de Endopeptidases do Proteassoma/metabolismo; Proteólise; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; Receptores Depuradores Classe A/genética; Receptores Depuradores Classe A/metabolismo; Receptores Depuradores Classe E/genética; Receptores Depuradores Classe E/metabolismo; Transdução de Sinais; Irradiação Corporal Total

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoantígenos / Proteínas de Transporte / Complexo de Endopeptidases do Proteassoma / Aterosclerose / Fator 1 de Transcrição de Octâmero / Placa Aterosclerótica / Células Espumosas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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