Fine-tuning the (2S)-naringenin synthetic pathway using an iterative high-throughput balancing strategy.

Zhou, Shenghu; Lyu, Yunbin; Li, Huazhong; Koffas, Mattheos A G; Zhou, Jingwen

Zhou, Shenghu; Lyu, Yunbin; Li, Huazhong; Koffas, Mattheos A G; Zhou, Jingwen.

Afiliação

Zhou S; Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.
Lyu Y; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu, China.
Li H; Jiangsu Provisional Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi, Jiangsu, China.
Koffas MAG; Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.
Zhou J; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu, China.

Biotechnol Bioeng ; 116(6): 1392-1404, 2019 06.

Article em En | MEDLINE | ID: mdl-30684358

Assuntos

Vias Biossintéticas/genética; Flavanonas; Ensaios de Triagem em Larga Escala/métodos; Engenharia Metabólica/métodos; Aciltransferases; Escherichia coli/genética; Flavanonas/análise; Flavanonas/genética; Flavanonas/metabolismo; Plasmídeos/genética; Regiões Promotoras Genéticas/genética

Palavras-chave

flavonoids; metabolic engineering; modular optimization; promoter

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flavanonas / Vias Biossintéticas / Ensaios de Triagem em Larga Escala / Engenharia Metabólica Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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