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A Comparative Analysis of the Status Anxiety Hypothesis of Socio-economic Inequalities in Health Based on 18,349 individuals in Four Countries and Five Cohort Studies.
Layte, Richard; McCrory, Cathal; Cheallaigh, Cliona Ni; Bourke, Nollaig; Kivimaki, Mika; Ribeiro, Ana Isabel; Stringhini, Silvia; Vineis, Paolo.
Afiliação
  • Layte R; The Department of Sociology, School of Social Sciences and Philosophy, Trinity College Dublin, Dublin, Ireland. layter@tcd.ie.
  • McCrory C; The Irish Longitudinal Study on Ageing (TILDA), Trinity College Dublin, Dublin, Ireland.
  • Cheallaigh CN; Centre for Medical Gerontology, Trinity College Dublin, Dublin, Ireland.
  • Bourke N; Centre for Medical Gerontology, Trinity College Dublin, Dublin, Ireland.
  • Kivimaki M; Institute of Epidemiology & Health, University College London, London, UK.
  • Ribeiro AI; Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina, Universidade do Porto, Porto, Portugal & EPIUnit, Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
  • Stringhini S; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.
  • Vineis P; MRC-PHE Centre for Environment and Health, School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Sci Rep ; 9(1): 796, 2019 01 28.
Article em En | MEDLINE | ID: mdl-30692559
The status anxiety hypothesis proposes that systematic inflammation as a consequence of chronic psycho-social stress is a possible pathway linking socio-economic position (SEP) to premature ageing and is a possible explanation for cross-national variation in patterns of health and well-being. Harmonised data from the LIFEPATH consortium on 18,349 individuals aged 50 to 75 and 30,632 observations are used to measure variation in the association between inflammation measured as C-reactive protein and SEP across four countries (Britain, Ireland, Portugal and Switzerland) and five studies (ELSA, Whitehall II, TILDA, EPIPorto and SKIPOGH). Adjusting for population composition, mean concentrations of CRP are highest in Portugal, the country with the highest income inequality and lowest in Switzerland, a lower income inequality country. Across all of the studies, lower SEP groups have higher mean concentrations of CRP and, as predicted by the theory, absolute differentials between SEP groups reflect the pattern of societal income inequality. Adjustment for lifestyle indicators reduces SEP differentials by between 45% and 52% but cannot account for country variation in mean inflammation.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ansiedade / Pobreza / Proteína C-Reativa Tipo de estudo: Clinical_trials / Etiology_studies / Health_economic_evaluation / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ansiedade / Pobreza / Proteína C-Reativa Tipo de estudo: Clinical_trials / Etiology_studies / Health_economic_evaluation / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article