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Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo.
Xu, Xuezhen; Kwon, Ok-Kyoung; Shin, In-Sik; Mali, Jyotirling R; Harmalkar, Dipesh S; Lim, Yourim; Lee, Gilhye; Lu, Qili; Oh, Sei-Ryang; Ahn, Kyung-Seop; Jeong, Hye-Gwang; Lee, Kyeong.
Afiliação
  • Xu X; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea.
  • Kwon OK; Department of Toxicology, College of Pharmacy, Chungnam National University, Daejeon, 34134, Korea.
  • Shin IS; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungju-si, Chungbuk, 28116, Korea.
  • Mali JR; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Korea.
  • Harmalkar DS; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea.
  • Lim Y; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea.
  • Lee G; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungju-si, Chungbuk, 28116, Korea.
  • Lu Q; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungju-si, Chungbuk, 28116, Korea.
  • Oh SR; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea.
  • Ahn KS; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungju-si, Chungbuk, 28116, Korea.
  • Jeong HG; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungju-si, Chungbuk, 28116, Korea.
  • Lee K; Department of Toxicology, College of Pharmacy, Chungnam National University, Daejeon, 34134, Korea. hgjeong@cnu.ac.kr.
Sci Rep ; 9(1): 862, 2019 01 29.
Article em En | MEDLINE | ID: mdl-30696844
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Asma / Benzofuranos / Mucosa Respiratória / Macrófagos / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Asma / Benzofuranos / Mucosa Respiratória / Macrófagos / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article