Handheld line-scanned dual-axis confocal microscope with pistoned MEMS actuation for flat-field fluorescence imaging.
Opt Lett
; 44(3): 671-674, 2019 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-30702707
ABSTRACT
A handheld line-scanned dual-axis confocal (LS-DAC) microscope has been developed for high-speed (16 frames/s) fluorescence imaging of tissues with sub-nuclear resolution. This is the first miniature fluorescence LS-DAC system that has been fully packaged for handheld clinical use on patients. A novel micro-electro-mechanical system scanning mechanism, with synchronized tilting and pistoning, is used to achieve flat-field en face imaging. We show that this facilitates video mosaicking to generate images that sample an extended lateral field of view.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microscopia Confocal
/
Sistemas Microeletromecânicos
/
Imagem Óptica
Limite:
Animals
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article