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Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers.
Sijbesma, Eline; Hallenbeck, Kenneth K; Leysen, Seppe; de Vink, Pim J; Skóra, Lukasz; Jahnke, Wolfgang; Brunsveld, Luc; Arkin, Michelle R; Ottmann, Christian.
Afiliação
  • Sijbesma E; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Hallenbeck KK; Department of Pharmaceutical Chemistry and Small Molecule Discovery Centre (SMDC) , University of California , San Francisco 94143 , United States.
  • Leysen S; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • de Vink PJ; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Skóra L; Chemical Biology and Therapeutics , Novartis Institutes for Biomedical Research , CH-4056 Basel , Switzerland.
  • Jahnke W; Chemical Biology and Therapeutics , Novartis Institutes for Biomedical Research , CH-4056 Basel , Switzerland.
  • Brunsveld L; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Arkin MR; Department of Pharmaceutical Chemistry and Small Molecule Discovery Centre (SMDC) , University of California , San Francisco 94143 , United States.
  • Ottmann C; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
J Am Chem Soc ; 141(8): 3524-3531, 2019 02 27.
Article em En | MEDLINE | ID: mdl-30707565
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas 14-3-3 / Receptor alfa de Estrogênio / Descoberta de Drogas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas 14-3-3 / Receptor alfa de Estrogênio / Descoberta de Drogas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article