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2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells.
Li, Wuguo; Zhang, Qing; Chen, Kaotan; Sima, Zhenhua; Liu, Jingli; Yu, Qiang; Liu, Jiawei.
Afiliação
  • Li W; Ministry of Education Key Laboratory of Chinese Medicinal Resource from Lingnan, Research Center of Medicinal Plant Resource Science and Engineering, Guangzhou University of Chinese Medicine, 232 Waihuandong Road, Higher Education Mega Center, Guangzhou, 510006, China.
  • Zhang Q; Animal Experiment Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People's Republic of China.
  • Chen K; Departments of Pharmacology, , Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Rd., Zhangjiang Hi-Tech Park, Shanghai, 201203, People's Republic of China.
  • Sima Z; Ministry of Education Key Laboratory of Chinese Medicinal Resource from Lingnan, Research Center of Medicinal Plant Resource Science and Engineering, Guangzhou University of Chinese Medicine, 232 Waihuandong Road, Higher Education Mega Center, Guangzhou, 510006, China.
  • Liu J; Ministry of Education Key Laboratory of Chinese Medicinal Resource from Lingnan, Research Center of Medicinal Plant Resource Science and Engineering, Guangzhou University of Chinese Medicine, 232 Waihuandong Road, Higher Education Mega Center, Guangzhou, 510006, China.
  • Yu Q; Departments of Pharmacology, , Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Rd., Zhangjiang Hi-Tech Park, Shanghai, 201203, People's Republic of China.
  • Liu J; Departments of Pharmacology, , Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Rd., Zhangjiang Hi-Tech Park, Shanghai, 201203, People's Republic of China. qyu@sibs.ac.cn.
BMC Complement Altern Med ; 19(1): 38, 2019 Feb 01.
Article em En | MEDLINE | ID: mdl-30709346
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Naftoquinonas / Apoptose / Fallopia japonica / Proliferação de Células / Fator de Transcrição STAT3 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Naftoquinonas / Apoptose / Fallopia japonica / Proliferação de Células / Fator de Transcrição STAT3 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article