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New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment.
Chioua, Mourad; Martínez-Alonso, Emma; Gonzalo-Gobernado, Rafael; Ayuso, Maria I; Escobar-Peso, Alejandro; Infantes, Lourdes; Hadjipavlou-Litina, Dimitra; Montoya, Juan J; Montaner, Joan; Alcázar, Alberto; Marco-Contelles, José.
Afiliação
  • Chioua M; Laboratory of Medicinal Chemistry , IQOG, CSIC , C/Juan de la Cierva 3 , Madrid 28006 , Spain.
  • Martínez-Alonso E; Department of Investigation , IRYCIS, Hospital Ramón y Cajal , Ctra. Colmenar km 9.1 , Madrid 28034 , Spain.
  • Gonzalo-Gobernado R; Neurovascular Research Group , Institute of Biomedicine of Seville, IBiS, Hospital Universitario Virgen del Rocío , Av. Manuel Siurot s/n , Seville 41013 , Spain.
  • Ayuso MI; Neurovascular Research Group , Institute of Biomedicine of Seville, IBiS, Hospital Universitario Virgen del Rocío , Av. Manuel Siurot s/n , Seville 41013 , Spain.
  • Escobar-Peso A; Laboratory of Medicinal Chemistry , IQOG, CSIC , C/Juan de la Cierva 3 , Madrid 28006 , Spain.
  • Infantes L; Department of Investigation , IRYCIS, Hospital Ramón y Cajal , Ctra. Colmenar km 9.1 , Madrid 28034 , Spain.
  • Hadjipavlou-Litina D; Institute of Physical-Chemistry Rocasolano, CSIC , C/Serrano 119 , Madrid 28006 , Spain.
  • Montoya JJ; Department of Pharmaceutical Chemistry, School of Pharmacy , Aristotle University of Thessaloniki , Thessaloniki 54124 , Greece.
  • Montaner J; Isquaemia Biotech SL , Scientific Technological Park, C/Astrónoma Cecilia Payne s/n , Córdoba 14014 , Spain.
  • Alcázar A; Neurovascular Research Group , Institute of Biomedicine of Seville, IBiS, Hospital Universitario Virgen del Rocío , Av. Manuel Siurot s/n , Seville 41013 , Spain.
  • Marco-Contelles J; Department of Neurology , Hospital Universitario Virgen Macarena , Av. Doctor Fedriani 3 , Seville 41007 , Spain.
J Med Chem ; 62(4): 2184-2201, 2019 02 28.
Article em En | MEDLINE | ID: mdl-30715875
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Ataque Isquêmico Transitório / Sequestradores de Radicais Livres / Fármacos Neuroprotetores / Iminas Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Ataque Isquêmico Transitório / Sequestradores de Radicais Livres / Fármacos Neuroprotetores / Iminas Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article