Neglected Cells: Immunomodulatory Roles of CD71<sup>+</sup> Erythroid Cells.

Elahi, Shokrollah

Neglected Cells: Immunomodulatory Roles of CD71⁺ Erythroid Cells.

Elahi, Shokrollah.

Afiliação

Elahi S; Department of Dentistry and Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada; Li Ka Shing Institute of Virology, Faculty of Medicine and Dentistry, University of Alberta, AB T6G2E1, Canada. Electronic address: elahi@ualberta.ca.

Trends Immunol ; 40(3): 181-185, 2019 03.

Article em En | MEDLINE | ID: mdl-30718046

ABSTRACT

ABSTRACT

The main role of red blood cells is oxygen-transportation. However, recent studies have unveiled immunomodulatory functions for their immature counterparts, CD71+ erythroid cells, under different physiological and pathological conditions. Here, I provide a perspective on the recent advances in this field to highlight their importance in health and disease.

Assuntos

Eritrócitos/fisiologia; Células Eritroides/citologia; Linfócitos T Reguladores/imunologia; Animais; Antígenos CD/metabolismo; Diferenciação Celular; Microambiente Celular; Células Eritroides/metabolismo; Desenvolvimento Fetal; Humanos; Imunomodulação; Ativação Linfocitária; Camundongos; Receptores da Transferrina/metabolismo

Palavras-chave

CD71(+) erythroid cells; immature red blood cells; immunosuppression; nucleated erythrocytes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Reguladores / Células Eritroides / Eritrócitos Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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