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Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors.
Seth, Sahil; Li, Chieh-Yuan; Ho, I-Lin; Corti, Denise; Loponte, Sara; Sapio, Luigi; Del Poggetto, Edoardo; Yen, Er-Yen; Robinson, Frederick Scott; Peoples, Michael; Karpinets, Tatiana; Deem, Angela Kay; Kumar, Tapsi; Song, Xingzhi; Jiang, Shan; Kang, Ya'an; Fleming, Jason; Kim, Michael; Zhang, Jianhua; Maitra, Anirban; Heffernan, Timothy Paul; Giuliani, Virginia; Genovese, Giannicola; Futreal, Andrew; Draetta, Giulio Francesco; Carugo, Alessandro; Viale, Andrea.
Afiliação
  • Seth S; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Li CY; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ho IL; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Corti D; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Loponte S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sapio L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Del Poggetto E; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Yen EY; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Robinson FS; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Peoples M; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Karpinets T; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Deem AK; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kumar T; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Song X; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jiang S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kang Y; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Fleming J; Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA.
  • Kim M; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhang J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Maitra A; Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Heffernan TP; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Giuliani V; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Genovese G; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Futreal A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Draetta GF; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Carugo A; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: acarugo@mdanderson.org.
  • Viale A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: aviale@mdanderson.org.
Cell Rep ; 26(6): 1518-1532.e9, 2019 02 05.
Article em En | MEDLINE | ID: mdl-30726735
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Heterogeneidade Genética / Resistencia a Medicamentos Antineoplásicos / Transcriptoma Limite: Aged / Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Heterogeneidade Genética / Resistencia a Medicamentos Antineoplásicos / Transcriptoma Limite: Aged / Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article