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Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Vousden, Katherine A; Lundqvist, Tomas; Popovic, Bojana; Naiman, Brian; Carruthers, Alan M; Newton, Philip; Johnson, Daniel J D; Pomowski, Anja; Wilkinson, Trevor; Dufner, Patrick; de Mendez, Isabelle; Mallinder, Philip R; Murray, Clare; Strain, Martin; Connor, Jane; Murray, Lynne A; Sleeman, Matthew A; Lowe, David C; Huntington, James A; Vaughan, Tristan J.
Afiliação
  • Vousden KA; MedImmune Ltd, Cambridge, CB21 6GH, UK. vousdenk@medimmune.com.
  • Lundqvist T; AstraZeneca AB R&D, Pepparedsleden 1, 431 50, Mölndal, Sweden.
  • Popovic B; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Naiman B; MedImmune LLC, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Carruthers AM; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Newton P; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Johnson DJD; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Pomowski A; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Wilkinson T; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Dufner P; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • de Mendez I; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Mallinder PR; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Murray C; AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire, SK10 4TF, UK.
  • Strain M; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Connor J; MedImmune LLC, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Murray LA; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Sleeman MA; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Lowe DC; MedImmune Ltd, Cambridge, CB21 6GH, UK.
  • Huntington JA; Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Vaughan TJ; MedImmune Ltd, Cambridge, CB21 6GH, UK.
Sci Rep ; 9(1): 1605, 2019 02 07.
Article em En | MEDLINE | ID: mdl-30733557
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidor 1 de Ativador de Plasminogênio / Anticorpos Neutralizantes Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidor 1 de Ativador de Plasminogênio / Anticorpos Neutralizantes Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article