Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells.

Coliva, Giulia; Duarte, Sofia; Pérez-Sala, Dolores; Fedorova, Maria

Coliva, Giulia; Duarte, Sofia; Pérez-Sala, Dolores; Fedorova, Maria.

Afiliação

Coliva G; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany; Center for Biotechnology and Biomedicine, University of Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany.
Duarte S; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, C.S.I.C., 28040 Madrid, Spain.
Pérez-Sala D; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, C.S.I.C., 28040 Madrid, Spain.
Fedorova M; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany; Center for Biotechnology and Biomedicine, University of Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany. Electronic address: maria.fedorova@bbz.uni-leipzig.

Redox Biol ; 23: 101123, 2019 05.

Article em En | MEDLINE | ID: mdl-30737170

Assuntos

Autofagia; Lisossomos/metabolismo; Miócitos Cardíacos/metabolismo; Proteoma/metabolismo; Transdução de Sinais; Animais; Células Cultivadas; Metabolismo dos Lipídeos; Oxirredução; Estresse Oxidativo; Carbonilação Proteica; Proteômica/métodos; Ratos; Estresse Fisiológico

Palavras-chave

Autophagy-lysosomal flux; Cellular stress; Protein and lipids carbonylation; Protein lipoxidation; Proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Transdução de Sinais / Proteoma / Miócitos Cardíacos / Lisossomos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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