Mucosal boosting of H56:CAF01 immunization promotes lung-localized T cells and an accelerated pulmonary response to Mycobacterium tuberculosis infection without enhancing vaccine protection.

Woodworth, Joshua S; Christensen, Dennis; Cassidy, Joseph P; Agger, Else Marie; Mortensen, Rasmus; Andersen, Peter

Woodworth, Joshua S; Christensen, Dennis; Cassidy, Joseph P; Agger, Else Marie; Mortensen, Rasmus; Andersen, Peter.

Afiliação

Woodworth JS; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark. jow@ssi.dk.
Christensen D; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.
Cassidy JP; Veterinary Sciences Centre, School of Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland.
Agger EM; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.
Mortensen R; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.
Andersen P; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.

Mucosal Immunol ; 12(3): 816-826, 2019 05.

Article em En | MEDLINE | ID: mdl-30760832

Assuntos

Vacina BCG/imunologia; Pulmão/imunologia; Mycobacterium tuberculosis/fisiologia; Células Th1/imunologia; Células Th17/imunologia; Tuberculose Pulmonar/imunologia; Animais; Modelos Animais de Doenças; Humanos; Imunização Secundária; Memória Imunológica; Pulmão/microbiologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C3H; Camundongos Endogâmicos C57BL

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vacina BCG / Células Th1 / Células Th17 / Pulmão / Mycobacterium tuberculosis Tipo de estudo: Guideline Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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