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Synthesis, docking and antibacterial studies of more potent amine and hydrazone rifamycin congeners than rifampicin.
Pyta, Krystian; Janas, Anna; Szukowska, Monika; Pecyna, Paulina; Jaworska, Marcelina; Gajecka, Marzena; Bartl, Franz; Przybylski, Piotr.
Afiliação
  • Pyta K; Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614, Poznan, Poland.
  • Janas A; Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614, Poznan, Poland.
  • Szukowska M; Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614, Poznan, Poland.
  • Pecyna P; Department of Genetics and Pharmaceutical Microbiology, University of Medical Sciences, Swiecickiego 4, 60-781, Poznan, Poland.
  • Jaworska M; Department of Genetics and Pharmaceutical Microbiology, University of Medical Sciences, Swiecickiego 4, 60-781, Poznan, Poland.
  • Gajecka M; Department of Genetics and Pharmaceutical Microbiology, University of Medical Sciences, Swiecickiego 4, 60-781, Poznan, Poland; Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland.
  • Bartl F; Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, Institut für Biologie, Biophysikalische Chemie, Invalidenstr. 42, 10099, Berlin, Germany.
  • Przybylski P; Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614, Poznan, Poland. Electronic address: piotrp@amu.edu.pl.
Eur J Med Chem ; 167: 96-104, 2019 Apr 01.
Article em En | MEDLINE | ID: mdl-30769243
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifamicinas / Simulação de Acoplamento Molecular / Aminas / Hidrazonas / Antibacterianos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifamicinas / Simulação de Acoplamento Molecular / Aminas / Hidrazonas / Antibacterianos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article