Simvastatin promotes restoration of chondrocyte morphology and phenotype.

Terabe, Kenya; Takahashi, Nobunori; Cobb, Michelle; Askew, Emily B; Knudson, Cheryl B; Knudson, Warren

Terabe, Kenya; Takahashi, Nobunori; Cobb, Michelle; Askew, Emily B; Knudson, Cheryl B; Knudson, Warren.

Afiliação

Terabe K; Department of Anatomy and Cell Biology, East Carolina University, 600 Moye Blvd., Greenville, NC, 27834, USA.
Takahashi N; Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Japan.
Cobb M; Department of Anatomy and Cell Biology, East Carolina University, 600 Moye Blvd., Greenville, NC, 27834, USA.
Askew EB; Department of Anatomy and Cell Biology, East Carolina University, 600 Moye Blvd., Greenville, NC, 27834, USA.
Knudson CB; Department of Anatomy and Cell Biology, East Carolina University, 600 Moye Blvd., Greenville, NC, 27834, USA.
Knudson W; Department of Anatomy and Cell Biology, East Carolina University, 600 Moye Blvd., Greenville, NC, 27834, USA. Electronic address: knudsonw@ecu.edu.

Arch Biochem Biophys ; 665: 1-11, 2019 04 15.

Article em En | MEDLINE | ID: mdl-30776329

Assuntos

Condrócitos/efeitos dos fármacos; Sinvastatina/farmacologia; Animais; Bovinos; Células Cultivadas; Humanos; Ratos

Palavras-chave

Aggrecan; Chondrocyte; Osteoarthritis; Prenylation; SOX9; Simvastatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Condrócitos / Sinvastatina Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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