In prenatally diagnosed CPAM, does the affected lobe influence the timing of symptom onset?
Pediatr Surg Int
; 35(5): 559-563, 2019 May.
Article
em En
| MEDLINE
| ID: mdl-30778700
ABSTRACT
PURPOSE:
We investigated the relationship between the affected lobe and symptom onset in prenatally diagnosed congenital pulmonary airway malformation (CPAM).METHODS:
53 CPAM patients diagnosed prenatally were reviewed retrospectively by creating 2 groups according to symptom onset. Group Sneo (symptomatic during the neonatal period; n = 13) and group S > neo (symptomatic after the neonatal period; n = 40) were compared for type of CPAM, affected lobes, types of symptoms/infections, treatment, duration of follow-up, and histopathology. Requirement for surgery (Sx) was then used to create three subgroups Sneo + Sx, S > neo + Sx, and Sx-.RESULTS:
Some cases had multiple affected lobes. In Sneo, symptoms developed in 55.6%, 50.0%, 0%, 0%, and 36.8% of right upper lobes (RUL), right middle lobes (RML), right lower lobes (RLL), left upper lobes (LUL), and left lower lobes (LLL) diagnosed with CPAM, prenatally. In S > neo, symptoms developed in 0%, 0%, 6.3%, 55.6%, and 33.3% of RUL, RML, RLL, LUL, and LLL diagnosed with CPAM, prenatally.CONCLUSION:
In prenatally diagnosed CPAM, RUL and RML lesions are more likely to become symptomatic in neonates, and LUL lesions in infants. Surgery is recommended before the onset of respiratory infections after 1 year of age.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Malformação Adenomatoide Cística Congênita do Pulmão
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Ultrassonografia Pré-Natal
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Lateralidade Funcional
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Pulmão
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article