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The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Carmona-Gutierrez, Didac; Zimmermann, Andreas; Kainz, Katharina; Pietrocola, Federico; Chen, Guo; Maglioni, Silvia; Schiavi, Alfonso; Nah, Jihoon; Mertel, Sara; Beuschel, Christine B; Castoldi, Francesca; Sica, Valentina; Trausinger, Gert; Raml, Reingard; Sommer, Cornelia; Schroeder, Sabrina; Hofer, Sebastian J; Bauer, Maria A; Pendl, Tobias; Tadic, Jelena; Dammbrueck, Christopher; Hu, Zehan; Ruckenstuhl, Christoph; Eisenberg, Tobias; Durand, Sylvere; Bossut, Noélie; Aprahamian, Fanny; Abdellatif, Mahmoud; Sedej, Simon; Enot, David P; Wolinski, Heimo; Dengjel, Jörn; Kepp, Oliver; Magnes, Christoph; Sinner, Frank; Pieber, Thomas R; Sadoshima, Junichi; Ventura, Natascia; Sigrist, Stephan J; Kroemer, Guido; Madeo, Frank.
Afiliação
  • Carmona-Gutierrez D; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Zimmermann A; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Kainz K; Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, 8036, Austria.
  • Pietrocola F; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Chen G; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
  • Maglioni S; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France.
  • Schiavi A; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Nah J; Université Pierre et Marie Curie, Paris, France.
  • Mertel S; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
  • Beuschel CB; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France.
  • Castoldi F; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Sica V; Université Pierre et Marie Curie, Paris, France.
  • Trausinger G; IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, 40225, Germany.
  • Raml R; IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, 40225, Germany.
  • Sommer C; Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
  • Schroeder S; Institute for Biology/Genetics, Freie Universität Berlin, Berlin, 14195, Germany.
  • Hofer SJ; Institute for Biology/Genetics, Freie Universität Berlin, Berlin, 14195, Germany.
  • Bauer MA; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
  • Pendl T; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France.
  • Tadic J; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Dammbrueck C; Université Pierre et Marie Curie, Paris, France.
  • Hu Z; Sotio a.c, 17000, Prague, Czech Republic.
  • Ruckenstuhl C; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
  • Eisenberg T; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France.
  • Durand S; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Bossut N; Université Pierre et Marie Curie, Paris, France.
  • Aprahamian F; Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, 8010, Austria.
  • Abdellatif M; Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, 8010, Austria.
  • Sedej S; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Enot DP; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Wolinski H; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Dengjel J; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Kepp O; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Magnes C; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Sinner F; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Pieber TR; Department of Cardiology, Medical University of Graz, Graz, 8036, Austria.
  • Sadoshima J; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Ventura N; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, 8010, Austria.
  • Sigrist SJ; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
  • Kroemer G; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France.
  • Madeo F; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.
Nat Commun ; 10(1): 651, 2019 02 19.
Article em En | MEDLINE | ID: mdl-30783116
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Flavonoides / Envelhecimento / Longevidade Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Flavonoides / Envelhecimento / Longevidade Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article