C1-esterase inhibitor enhances thrombin generation and spatial fibrin clot propagation in the presence of thrombomodulin.

Tarandovskiy, Ivan D; Buehler, Paul W; Ataullakhanov, Fazoil I; Karnaukhova, Elena

Tarandovskiy, Ivan D; Buehler, Paul W; Ataullakhanov, Fazoil I; Karnaukhova, Elena.

Afiliação

Tarandovskiy ID; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, United States. Electronic address: ivan.tarandovskiy@fda.hhs.gov.
Buehler PW; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, United States.
Ataullakhanov FI; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Kosygina str., 4, Moscow 119334, Russia.
Karnaukhova E; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, United States.

Thromb Res ; 176: 54-60, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30784776

Assuntos

Proteína Inibidora do Complemento C1/metabolismo; Fibrina/metabolismo; Trombina/metabolismo; Trombomodulina/metabolismo; Trombose/metabolismo; Coagulação Sanguínea; Proteína Inibidora do Complemento C1/análise; Fibrina/análise; Humanos; Trombina/análise; Trombomodulina/análise; Trombose/sangue

Palavras-chave

C1-inhibitor; Hereditary angioedem; Protein C; Thrombin generation; Thrombodynamics; Thrombomodulin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Fibrina / Trombina / Trombomodulina / Proteína Inibidora do Complemento C1 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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