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Identification of a new inhibitor of KRAS-PDEδ interaction targeting KRAS mutant nonsmall cell lung cancer.
Leung, Elaine Lai-Han; Luo, Lian Xiang; Li, Ying; Liu, Zhong-Qiu; Li, Lan Lan; Shi, Dan Feng; Xie, Ying; Huang, Min; Lu, Lin Lin; Duan, Fu Gang; Huang, Ju Min; Fan, Xing Xing; Yuan, Zhong Wen; Ding, Jian; Yao, Xiao Jun; Ward, David C; Liu, Liang.
Afiliação
  • Leung EL; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Luo LX; Department of Thoracic Surgery, State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Li Y; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Liu ZQ; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Li LL; International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Shi DF; State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, China.
  • Xie Y; State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, China.
  • Huang M; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Lu LL; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academic of Sciences, Shanghai, China.
  • Duan FG; International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Huang JM; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Fan XX; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Yuan ZW; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Ding J; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Yao XJ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academic of Sciences, Shanghai, China.
  • Ward DC; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau (SAR), China.
  • Liu L; State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, China.
Int J Cancer ; 145(5): 1334-1345, 2019 09 01.
Article em En | MEDLINE | ID: mdl-30786019
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Carcinoma Pulmonar de Células não Pequenas / Nucleotídeo Cíclico Fosfodiesterase do Tipo 6 / Hidrazonas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Carcinoma Pulmonar de Células não Pequenas / Nucleotídeo Cíclico Fosfodiesterase do Tipo 6 / Hidrazonas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article