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In vitro and in vivo pharmacokinetics and metabolism of MK-8353 by liquid chromatography combined with diode array detector and Q-Exactive-Orbitrap tandem mass spectrometry.
Gong, Jingru; Jiang, Zhe; Yang, Tao; Zhu, Yahong.
Afiliação
  • Gong J; Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, No. 2800 Gongwei Road, Pudong, Shanghai, 201399, China.
  • Jiang Z; Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, No. 2800 Gongwei Road, Pudong, Shanghai, 201399, China.
  • Yang T; Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, No. 2800 Gongwei Road, Pudong, Shanghai, 201399, China.
  • Zhu Y; Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, No. 2800 Gongwei Road, Pudong, Shanghai, 201399, China. Electronic address: zhu_yahong@126.com.
J Pharm Biomed Anal ; 168: 64-74, 2019 May 10.
Article em En | MEDLINE | ID: mdl-30797103
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Pirrolidinas / Triazóis / Cromatografia Líquida / Inibidores de Proteínas Quinases / Espectrometria de Massas em Tandem / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Pirrolidinas / Triazóis / Cromatografia Líquida / Inibidores de Proteínas Quinases / Espectrometria de Massas em Tandem / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article