Compilation of Modern Technologies To Map Genome-Wide Cytosine Modifications in DNA.
Chembiochem
; 20(15): 1898-1905, 2019 08 01.
Article
em En
| MEDLINE
| ID: mdl-30809902
ABSTRACT
Over the past few decades, various DNA modification detection methods have been developed; many of the high-resolution methods are based on bisulfite treatment, which leads to DNA degradation, to a degree. Thus, novel bisulfite-free approaches have been developed in recent years and shown to be useful for epigenome analysis in otherwise difficult-to-handle, but important, DNA samples, such as hmC-seal and hmC-CATCH. Herein, an overview of advances in the development of epigenome sequencing methods for these important DNA modifications is provided.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Citosina
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article