Anti-Ly-1 antibody induces interleukin 2 release from T cells.
J Immunol
; 136(5): 1734-7, 1986 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-3081630
ABSTRACT
In this report we show that a signal provided by binding of anti-Ly-1 antibody to the Ly-1 cell surface protein, along with a second signal provided by mitogen, can trigger a T cell into activation and increase [Ca2+]i and the release of IL2. At optimal concentrations, the effects of anti-Ly-1 and IL 1 are additive, suggesting a different activation pathway for each.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
/
Interleucina-2
/
Isoanticorpos
Limite:
Animals
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article