Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation.

Kresinsky, Anne; Schnöder, Tina M; Jacobsen, Ilse D; Rauner, Martina; Hofbauer, Lorenz C; Ast, Volker; König, Rainer; Hoffmann, Bianca; Svensson, Carl-Magnus; Figge, Marc Thilo; Hilger, Ingrid; Heidel, Florian H; Böhmer, Frank- D; Müller, Jörg P

Kresinsky, Anne; Schnöder, Tina M; Jacobsen, Ilse D; Rauner, Martina; Hofbauer, Lorenz C; Ast, Volker; König, Rainer; Hoffmann, Bianca; Svensson, Carl-Magnus; Figge, Marc Thilo; Hilger, Ingrid; Heidel, Florian H; Böhmer, Frank- D; Müller, Jörg P.

Afiliação

Kresinsky A; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), Jena University Hospital, Jena, Germany.
Schnöder TM; Internal medicine II, Department of Haematology and Oncology, Jena University Hospital, Jena, Germany.
Jacobsen ID; Research Group Microbial Immunology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Rauner M; Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany.
Hofbauer LC; Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany.
Ast V; Network modelling, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
König R; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Am Klinikum 1, Jena, 07747, Germany.
Hoffmann B; Network modelling, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Svensson CM; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Am Klinikum 1, Jena, 07747, Germany.
Figge MT; Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Hilger I; Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Heidel FH; Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Böhmer FD; Faculty of Biological Sciences, Friedrich Schiller University Jena, Jena, Germany.
Müller JP; Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany.

Oncogene ; 38(24): 4773-4787, 2019 06.

Article em En | MEDLINE | ID: mdl-30820040

Assuntos

Osso e Ossos; Antígenos Comuns de Leucócito/genética; Transtornos Mieloproliferativos/genética; Osteoporose/genética; Tirosina Quinase 3 Semelhante a fms/genética; Animais; Desenvolvimento Ósseo/genética; Remodelação Óssea/genética; Transformação Celular Neoplásica; Células Cultivadas; Coristoma/genética; Coristoma/metabolismo; Embrião de Mamíferos; Feminino; Humanos; Leucemia Mieloide Aguda/complicações; Leucemia Mieloide Aguda/genética; Leucemia Mieloide Aguda/patologia; Antígenos Comuns de Leucócito/deficiência; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Mutação; Transtornos Mieloproliferativos/complicações; Transtornos Mieloproliferativos/patologia; Osteogênese/genética; Osteoporose/metabolismo; Osteoporose/patologia; Fenótipo; Porosidade; Sequências de Repetição em Tandem/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoporose / Osso e Ossos / Antígenos Comuns de Leucócito / Tirosina Quinase 3 Semelhante a fms / Transtornos Mieloproliferativos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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