The burden of chronic urticaria: French baseline data from the international real-life AWARE study.
Eur J Dermatol
; 29(1): 49-54, 2019 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-30827942
ABSTRACT
BACKGROUND:
The AWARE study is an ongoing international study of patients with chronic urticaria refractory to H1-antihistamines. The aim of this study is to evaluate the burden of disease and the use of healthcare resources in real-life conditions.OBJECTIVES:
To analyse the baseline data of French patients included in the AWARE study. MATERIALS &METHODS:
AWARE is a prospective, non-interventional, international study that includes adult patients who have had chronic urticaria, refractory to at least one H1-antihistamine, for at least two months.RESULTS:
Ninety-four patients (mean age 47.9 years; 71.3% women) with chronic urticaria (50.0% spontaneous only, 9.6% inducible only, and 40.4% both) were included in French centres. The median duration from diagnosis was three years and angioedema was present in 31.5% of patients for the past six months. In 63.8% of cases, the patients received at least one treatment for urticaria (H1-antihistamine for 66.0%). Chronic urticaria was poorly controlled (UCT score <12) in 88.9% of patients and quality of life was severely impaired (mean DLQI score 8.6). The use of healthcare resources was significant with frequent visits to general practitioners (80.8% of patients; mean 8.1 visits). However, more than half of patients had not previously consulted a dermatologist.CONCLUSION:
These baseline data of French patients in the AWARE study show that patients suffering from chronic urticaria, refractory to H1-antihistamines for a median of three years, are insufficiently treated and that their quality of life is impaired. Despite the significant use of healthcare resources, access to specialised consultations remains insufficient.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Urticária
/
Antagonistas dos Receptores Histamínicos H1
Tipo de estudo:
Observational_studies
Limite:
Adult
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Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article