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Clinical genome sequencing uncovers potentially targetable truncations and fusions of MAP3K8 in spitzoid and other melanomas.
Newman, Scott; Fan, Liying; Pribnow, Allison; Silkov, Antonina; Rice, Stephen V; Lee, Seungjae; Shao, Ying; Shaner, Bridget; Mulder, Heather; Nakitandwe, Joy; Shurtleff, Sheila; Azzato, Elizabeth M; Wu, Gang; Zhou, Xin; Barnhill, Raymond; Easton, John; Nichols, Kim E; Ellison, David W; Downing, James R; Pappo, Alberto; Potter, Philip M; Zhang, Jinghui; Bahrami, Armita.
Afiliação
  • Newman S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. scott.newman@stjude.org.
  • Fan L; Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Pribnow A; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Silkov A; Department of Pediatrics, Division of Hematology/Oncology, Stanford University School of Medicine, Palo Alto, CA, USA.
  • Rice SV; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Lee S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Shao Y; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Shaner B; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Mulder H; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Nakitandwe J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Shurtleff S; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Azzato EM; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wu G; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Zhou X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Barnhill R; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Easton J; Departments of Pathology and Translational Research, Institute Curie, Paris, France.
  • Nichols KE; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Ellison DW; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Downing JR; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Pappo A; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Potter PM; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Zhang J; Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Bahrami A; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. jinghui.zhang@stjude.org.
Nat Med ; 25(4): 597-602, 2019 04.
Article em En | MEDLINE | ID: mdl-30833747
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Humano / Proteínas Proto-Oncogênicas / Análise de Sequência de DNA / MAP Quinase Quinase Quinases / Melanoma Limite: Animals / Child / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Humano / Proteínas Proto-Oncogênicas / Análise de Sequência de DNA / MAP Quinase Quinase Quinases / Melanoma Limite: Animals / Child / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article