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Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery.
Taguchi, Tomoaki; Yanagi, Yusuke; Yoshimaru, Koichiro; Zhang, Xiu-Ying; Matsuura, Toshiharu; Nakayama, Koichi; Kobayashi, Eiji; Yamaza, Haruyoshi; Nonaka, Kazuaki; Ohga, Shouichi; Yamaza, Takayoshi.
Afiliação
  • Taguchi T; Department of Pediatric Surgery, Graduate School of Medical Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. taguchi@pedsurg.med.kyushu-u.ac.jp.
  • Yanagi Y; Department of Pediatric Surgery, Graduate School of Medical Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Yoshimaru K; Department of Pediatric Surgery, Graduate School of Medical Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Zhang XY; Department of Pediatric Surgery, Graduate School of Medical Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Matsuura T; Department of Pediatric Surgery, Graduate School of Medical Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Nakayama K; Department of Regenerative Medicine and Biomedical Engineering, Faculty of Medicine, Saga University, Honjyo 1-chome, Honjyo-cho, Saga, 840-8502, Japan.
  • Kobayashi E; Department of Organ Fabrication, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
  • Yamaza H; Department of Pediatric Dentistry, Graduate School of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Nonaka K; Department of Pediatric Dentistry, Graduate School of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Ohga S; Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Yamaza T; Department of Molecular Cell Biology and Oral Anatomy, Graduate School of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Surg Today ; 49(4): 316-322, 2019 Apr.
Article em En | MEDLINE | ID: mdl-30834983
ABSTRACT
Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pediatria / Células-Tronco / Dente Decíduo / Esfoliação de Dente / Engenharia Tecidual / Medicina Regenerativa / Terapia Baseada em Transplante de Células e Tecidos Limite: Animals / Child / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pediatria / Células-Tronco / Dente Decíduo / Esfoliação de Dente / Engenharia Tecidual / Medicina Regenerativa / Terapia Baseada em Transplante de Células e Tecidos Limite: Animals / Child / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article