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Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.
Harding, Rachel J; Loppnau, Peter; Ackloo, Suzanne; Lemak, Alexander; Hutchinson, Ashley; Hunt, Brittany; Holehouse, Alex S; Ho, Jolene C; Fan, Lixin; Toledo-Sherman, Leticia; Seitova, Alma; Arrowsmith, Cheryl H.
Afiliação
  • Harding RJ; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada, Rachel.Harding@utoronto.ca.
  • Loppnau P; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Ackloo S; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Lemak A; the Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Hutchinson A; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Hunt B; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Holehouse AS; the Department of Biomedical Engineering and Center for Biological Systems Engineering, Washington University in Saint Louis, Saint Louis, Missouri 63130.
  • Ho JC; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Fan L; the Basic Science Program, Frederick National Laboratory for Cancer Research, SAXS Core of NCI, National Institutes of Health, Frederick, Maryland 21701, and.
  • Toledo-Sherman L; the CHDI Foundation, Los Angeles, California 90045.
  • Seitova A; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada.
  • Arrowsmith CH; From the Structural Genomics Consortium, University of Toronto, Ontario M5G 1L7, Canada, Cheryl.Arrowsmith@uhnresearch.ca.
J Biol Chem ; 294(17): 6986-7001, 2019 04 26.
Article em En | MEDLINE | ID: mdl-30842263
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Proteína Huntingtina / Mutação Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica / Proteína Huntingtina / Mutação Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article