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Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans.
Heusser, Karsten; Tank, Jens; Holz, Olaf; May, Marcus; Brinkmann, Julia; Engeli, Stefan; Diedrich, André; Framke, Theodor; Koch, Armin; Großhennig, Anika; Jan Danser, A H; Sweep, Fred C G J; Schindler, Christoph; Schwarz, Katharina; Krug, Norbert; Jordan, Jens; Hohlfeld, Jens M.
Afiliação
  • Heusser K; Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147, Cologne, Germany.
  • Tank J; Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147, Cologne, Germany.
  • Holz O; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), 30625, Hannover, Germany.
  • May M; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, 30625, Hannover, Germany.
  • Brinkmann J; MHH CRC Core Facility & Centre for Pharmacology and Toxicology, Hannover Medical School, 30625, Hannover, Germany.
  • Engeli S; Institute for Clinical Pharmacology, Hannover Medical School, 30625, Hannover, Germany.
  • Diedrich A; Kaufmännische Krankenkasse - KKH, Karl-Wiechert-Allee 61, 30625, Hannover, Germany.
  • Framke T; Institute for Clinical Pharmacology, Hannover Medical School, 30625, Hannover, Germany.
  • Koch A; Department of Medicine, Division of Clinical Pharmacology, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
  • Großhennig A; Institute of Biostatistics, Hannover Medical School, 30625, Hannover, Germany.
  • Jan Danser AH; Institute of Biostatistics, Hannover Medical School, 30625, Hannover, Germany.
  • Sweep FCGJ; Institute of Biostatistics, Hannover Medical School, 30625, Hannover, Germany.
  • Schindler C; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus Medical Center, 3015 GE, Rotterdam, The Netherlands.
  • Schwarz K; Department of Laboratory Medicine, Radboud University Medical Centre, 6500 HB, Nijmegen, The Netherlands.
  • Krug N; MHH CRC Core Facility & Centre for Pharmacology and Toxicology, Hannover Medical School, 30625, Hannover, Germany.
  • Jordan J; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), 30625, Hannover, Germany.
  • Hohlfeld JM; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), 30625, Hannover, Germany.
Sci Rep ; 9(1): 3641, 2019 03 06.
Article em En | MEDLINE | ID: mdl-30842540
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ozônio / Pneumonia / Sistema Nervoso Simpático / Norepinefrina / Exposição por Inalação / Poluentes Atmosféricos / Material Particulado Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ozônio / Pneumonia / Sistema Nervoso Simpático / Norepinefrina / Exposição por Inalação / Poluentes Atmosféricos / Material Particulado Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article