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Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.
Llinàs-Arias, Pere; Rosselló-Tortella, Margalida; López-Serra, Paula; Pérez-Salvia, Montserrat; Setién, Fernando; Marin, Silvia; Muñoz, Juan P; Junza, Alexandra; Capellades, Jordi; Calleja-Cervantes, María E; Ferreira, Humberto J; de Moura, Manuel Castro; Srbic, Marina; Martínez-Cardús, Anna; de la Torre, Carolina; Villanueva, Alberto; Cascante, Marta; Yanes, Oscar; Zorzano, Antonio; Moutinho, Catia; Esteller, Manel.
Afiliação
  • Llinàs-Arias P; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Rosselló-Tortella M; Centro de Investigacion Biomedica en Red Cancer (CIBERONC), Madrid, Spain.
  • López-Serra P; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Pérez-Salvia M; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Setién F; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Marin S; Centro de Investigacion Biomedica en Red Cancer (CIBERONC), Madrid, Spain.
  • Muñoz JP; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Junza A; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Barcelona, Spain.
  • Capellades J; Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain.
  • Calleja-Cervantes ME; CIBER of Liver and Digestive Diseases (CIBEREHD), Madrid, Spain.
  • Ferreira HJ; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Barcelona, Spain.
  • de Moura MC; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Srbic M; CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), Madrid, Spain.
  • Martínez-Cardús A; CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), Madrid, Spain.
  • de la Torre C; Metabolomics Platform, IISPV, Department of Electronic Engineering (DEEEA), Universitat Rovira i Virgili, Tarragona, Catalonia, Spain.
  • Villanueva A; CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), Madrid, Spain.
  • Cascante M; Metabolomics Platform, IISPV, Department of Electronic Engineering (DEEEA), Universitat Rovira i Virgili, Tarragona, Catalonia, Spain.
  • Yanes O; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Zorzano A; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Moutinho C; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
  • Esteller M; Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
JCI Insight ; 52019 03 07.
Article em En | MEDLINE | ID: mdl-30843871
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a Fosfato / Retículo Endoplasmático / Reprogramação Celular / Epigenômica / Degradação Associada com o Retículo Endoplasmático / Proteínas de Membrana / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a Fosfato / Retículo Endoplasmático / Reprogramação Celular / Epigenômica / Degradação Associada com o Retículo Endoplasmático / Proteínas de Membrana / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article