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Discovery of novel selective Janus kinase 2 (JAK2) inhibitors bearing a 1H-pyrazolo[3,4-d]pyrimidin-4-amino scaffold.
Yin, Yuan; Chen, Cheng-Juan; Yu, Ru-Nan; Shu, Lei; Zhang, Tian-Tai; Zhang, Da-Yong.
Afiliação
  • Yin Y; School of Science, China Pharmaceutical University, Nanjing, China.
  • Chen CJ; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Yu RN; School of Science, China Pharmaceutical University, Nanjing, China.
  • Shu L; School of Science, China Pharmaceutical University, Nanjing, China.
  • Zhang TT; Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: ttzhang@imm.ac.cn.
  • Zhang DY; School of Science, China Pharmaceutical University, Nanjing, China. Electronic address: cpuzdy@163.com.
Bioorg Med Chem ; 27(8): 1562-1576, 2019 04 15.
Article em En | MEDLINE | ID: mdl-30846405
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Desenho de Fármacos / Inibidores de Proteínas Quinases / Janus Quinase 2 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Desenho de Fármacos / Inibidores de Proteínas Quinases / Janus Quinase 2 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article