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Safety and effectiveness of sodium colistimethate-loaded nanostructured lipid carriers (SCM-NLC) against P. aeruginosa: in vitro and in vivo studies following pulmonary and intramuscular administration.
Pastor, Marta; Basas, Jana; Vairo, Claudia; Gainza, Garazi; Moreno-Sastre, María; Gomis, Xavier; Fleischer, Aarne; Palomino, Esther; Bachiller, Daniel; Gutiérrez, Francisco Borja; Aguirre, Jose Javier; Esquisabel, Amaia; Igartua, Manoli; Gainza, Eusebio; Hernandez, Rosa Maria; Gavaldà, Joan; Pedraz, José Luis.
Afiliação
  • Pastor M; BioPraxis Research AIE, R&D Department, Miñano (Araba), Spain.
  • Basas J; Antimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron, Barcelona, Spain.
  • Vairo C; BioPraxis Research AIE, R&D Department, Miñano (Araba), Spain; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain.
  • Gainza G; BioPraxis Research AIE, R&D Department, Miñano (Araba), Spain.
  • Moreno-Sastre M; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain.
  • Gomis X; Antimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron, Barcelona, Spain.
  • Fleischer A; Consejo Superior de Investigaciones Científicas (CSIC/IMEDEA), Esporles, Spain.
  • Palomino E; Consejo Superior de Investigaciones Científicas (CSIC/IMEDEA), Esporles, Spain.
  • Bachiller D; Consejo Superior de Investigaciones Científicas (CSIC/IMEDEA), Esporles, Spain.
  • Gutiérrez FB; Department of Pathological Anatomy, Hospital Universitario de Álava (HUA), Vitoria-Gasteiz, Spain.
  • Aguirre JJ; BioPraxis Research AIE, R&D Department, Miñano (Araba), Spain; Department of Pathological Anatomy, Hospital Universitario de Álava (HUA), Vitoria-Gasteiz, Spain.
  • Esquisabel A; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain.
  • Igartua M; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain.
  • Gainza E; BioPraxis Research AIE, R&D Department, Miñano (Araba), Spain.
  • Hernandez RM; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain.
  • Gavaldà J; Antimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron, Barcelona, Spain. Electronic address: joan.gavalda@vhir.org.
  • Pedraz JL; NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Vitoria-Gasteiz, Spain; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, Spain. Electronic address: joseluis.pedraz@ehu.e
Nanomedicine ; 18: 101-111, 2019 06.
Article em En | MEDLINE | ID: mdl-30849549
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Portadores de Fármacos / Colistina / Nanoestruturas / Lipídeos / Pulmão Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Portadores de Fármacos / Colistina / Nanoestruturas / Lipídeos / Pulmão Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article