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Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Storti, Federica; Klee, Katrin; Todorova, Vyara; Steiner, Regula; Othman, Alaa; van der Velde-Visser, Saskia; Samardzija, Marijana; Meneau, Isabelle; Barben, Maya; Karademir, Duygu; Pauzuolyte, Valda; Boye, Sanford L; Blaser, Frank; Ullmer, Christoph; Dunaief, Joshua L; Hornemann, Thorsten; Rohrer, Lucia; den Hollander, Anneke; von Eckardstein, Arnold; Fingerle, Jürgen; Maugeais, Cyrille; Grimm, Christian.
Afiliação
  • Storti F; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Klee K; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Todorova V; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.
  • Steiner R; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Othman A; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland.
  • van der Velde-Visser S; Institute of Clinical Chemistry, University of Zurich, Schlieren, Switzerland.
  • Samardzija M; Institute of Clinical Chemistry, University of Zurich, Schlieren, Switzerland.
  • Meneau I; Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.
  • Barben M; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Karademir D; Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.
  • Pauzuolyte V; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Boye SL; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Blaser F; Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.
  • Ullmer C; Lab for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Schlieren, Switzerland.
  • Dunaief JL; Department of Ophthalmology, University of Florida, Gainesville, United States.
  • Hornemann T; Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.
  • Rohrer L; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F Hoffmann-La Roche Ltd., Basel, Switzerland.
  • den Hollander A; Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, United States.
  • von Eckardstein A; Institute of Clinical Chemistry, University of Zurich, Schlieren, Switzerland.
  • Fingerle J; Institute of Clinical Chemistry, University of Zurich, Schlieren, Switzerland.
  • Maugeais C; Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.
  • Grimm C; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, Netherlands.
Elife ; 82019 03 13.
Article em En | MEDLINE | ID: mdl-30864945
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Degeneração Retiniana / Metabolismo dos Lipídeos / Epitélio Pigmentado da Retina / Transportador 1 de Cassete de Ligação de ATP / Membro 1 da Subfamília G de Transportadores de Cassetes de Ligação de ATP Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Degeneração Retiniana / Metabolismo dos Lipídeos / Epitélio Pigmentado da Retina / Transportador 1 de Cassete de Ligação de ATP / Membro 1 da Subfamília G de Transportadores de Cassetes de Ligação de ATP Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article