Polymorphism and Forensic Application Value of 71 Y-SNP Loci in Han Population of Northwest China.
Fa Yi Xue Za Zhi
; 35(1): 23-29, 2019 Feb.
Article
em En, Zh
| MEDLINE
| ID: mdl-30896115
ABSTRACT
OBJECTIVES:
To analyze the polymorphism of 71 SNP loci on Y chromosome in Han population of Northwest China, to assess its forensic application value, and to screen out Y-SNP loci for forensic examination of Han population in East, South, and Northwest China based on the integration of previous research results.METHODS:
Multiplex polymerase chain reaction ï¼PCRï¼ and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry ï¼MALDI-TOF-MSï¼ were performed on 71 Y-SNP loci of 202 unrelated Han male individuals in Northwest China. Gene diversity ï¼GDï¼ and haplotype diversity ï¼HDï¼ values were calculated, and then Y-SNP loci of Han population in East, South, and Northwest China were screened with the combination of data from previous research.RESULTS:
Among the detected 71 loci, 67 loci were polymorphic in the Northwest Han male population, with GD values 0.010 0-0.502 2. There were 22 and 25 loci with a moderate ï¼0.2≤GD<0.3ï¼ and high ï¼GD≥0.3ï¼ amount of genetic information, respectively. There were 26 loci for the Han communities in Northwest, South, and East China.CONCLUSIONS:
Y-SNP loci are potential in paternity testing and individual identification, as well as the judgement of population distribution and migration.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Cromossomos Humanos Y
/
Povo Asiático
Limite:
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
/
Zh
Ano de publicação:
2019
Tipo de documento:
Article